I Muppets venuti dallo spazio

Dave Goelz

Gonzo / Dr. Bunsen Honeydew / Waldorf / The Birdman (voice)

Steve Whitmire

Kermit the Frog / Rizzo the Rat / Beaker / Cosmic Fish #1 / Rainbow / Miss Piggy (assistant) (voice)

Bill Barretta

Pepe the Prawn / Bobo as Rentro / Johnny Fiama / Bubba the Rat / Cosmic Fish #2 (voice)

Jerry Nelson

Robin / Statler / Ubergonzo (voice)

Brian Henson

Dr. Phil Van Neuter / Sal Minella (voice)

Kevin Clash

Clifford (voice)

Frank Oz

Miss Piggy / Fozzie Bear / Animal / Sam the Eagle (voice)

Jeffrey Tambor

K. Edgar Singer

F. Murray Abraham

Noah

Rob Schneider

TV Producer

Josh Charles

Agent Barker

Ray Liotta

Gate Guard

David Arquette

Dr. Tucker

Andie MacDowell

Shelley Snipes

Kathy Griffin

Female Armed Guard